Leukemia risk prediction

Note, I have marked this module as a legacy module. That's not because it is wrong, merely because the content is somewhat information-poor. Specifically the overall GWAS-browser contains the same information.

The main forms of leukemia are Acute lymphoblastic leukemia (ALL), Chronic lymphocytic leukemia (CLL), Acute myelogenous leukemia (AML), and Chronic myelogenous leukemia (CML). Like most complex diseases, these have been investigated using the genome-wide association (GWAS) technology. Particularly for the CLL form, several genetic variants have been discovered that increase or decrease the lifetime risk of the disease.

The strong point of this approach is that it has provided insight into how commonly found genetic variants affects diseases of everybody, i.e. as opposed to single-family-specific rare genetics variants. This means that most GWAS findings readily have been replicated between separate studies of different patients.

The weak point of GWAS, however, is that findings typically only explain small fractions of the risk of each disease. This means that their actualy prognostic value still is somewhat limited. This is illstrated and explained here.

To run analysis input your user-id, or use the test-value of id_613z86871:

Genetic risk score for Leukemia